Summary Information
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| Diseases / List of Bacterial Diseases
/ Disease summary |
| Alternative Names |
- Human granulocytic anaplasmosis (HGA)
- Human anaplasmosis
|
| Disease Agents |
Anaplasma
(previously Ehrlichia ) phagocytophilum. (J1.40.w7,
J112.27.w1)
|
| Infectious
Agent(s) |
Anaplasma phagocytophilum
(Tenericutes (Lacking cell-walls) (Division)) |
| Non-infectious
Agent(s) |
-- |
| Physical
Agent(s) |
--
|
| General Description |
In Humans
- Human granulocytic ehrlichosis manifests as a moderate to severe febrile
illness. As well as fever (at least 37.6 °C), headache, myalgia, chills and general malaise are
the most commonly noted clinical features. (J1.38.w3,
J416.25.w1)
- Clinical laboratory findings in
the later stages include variable leucopaenia, anaemia and thrombocytopaenia. (J1.38.w3,
J416.25.w1)
Transmission
- Transmitted by ticks. (J1.38.w3,
J1.40.w7, J416.25.w1)
- ixodes dentatus (which does not bite humans) and Ixodes
dammani are competent vectors. (J91.68.w1)
|
| Further Information |
In Bears
- Antibodies to human granulocytic ehrlichosis (HGE), Ehrlichia sp.
were detected by indirect immunofluorescence assay in 81/381 (21%) sera from
free-ranging Ursus americanus - American black bear
in Pennsylvania, USA, November 1997. (J1.38.w3)
In Lagomorphs
- On Nantucket Island, Massachusetts, USA, about 66% of Sylvilagus floridanus - Eastern Cottontail rabbit
sampled were found to be seropositive by indirect fluorescent antibody test,
while evidence of active infection was found in about 27% (by PCR
amplification from blood or blood and spleen). (J91.68.w1)
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| Associated Techniques |
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| Host taxa groups /species |
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| Disease Author |
Dr Debra Bourne MA VetMB PhD MRCVS
(V.w5)
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